A comparison study of linear reconstruction techniques for diffuse optical tomographic imaging of absorption coefficient.
نویسندگان
چکیده
We compare, through simulations, the performance of four linear algorithms for diffuse optical tomographic reconstruction of the three-dimensional distribution of absorption coefficient within a highly scattering medium using the diffuse photon density wave approximation. The simulation geometry consisted of a coplanar array of sources and detectors at the boundary of a half-space medium. The forward solution matrix is both underdetermined, because we estimate many more absorption coefficient voxels than we have measurements, and ill-conditioned, due to the ill-posedness of the inverse problem. We compare two algebraic techniques, ART and SIRT, and two subspace techniques, the truncated SVD and CG algorithms. We compare three-dimensional reconstructions with two-dimensional reconstructions which assume all inhomogeneities are confined to a known horizontal slab, and we consider two 'object-based' error metrics in addition to mean square reconstruction error. We include a comparison using simulated data generated using a different FDFD method with the same inversion algorithms to indicate how our conclusions are affected in a somewhat more realistic scenario. Our results show that the subspace techniques are superior to the algebraic techniques in localization of inhomogeneities and estimation of their amplitude, that two-dimensional reconstructions are sensitive to underestimation of the object depth, and that an error measure based on a location parameter can be a useful complement to mean squared error.
منابع مشابه
Constrained Reconstruction Techniques for Diffuse Optical Tomography
Three-dimensional diffuse optical tomography (DOT) attempts to map in vivo tissue blood oxygenation and blood volume levels by reconstructing the spatial distribution of the optical absorption coefficient from intensity measurements on the surface of the body. This problem is typically ill-posed due to the large attenuation and scattering of the diffuse wave. In addition, certain applications, ...
متن کاملEffect of Shot Noise on Simultaneous Sensing in Frequency Division Multiplexed Diffuse Optical Tomographic Imaging Process
Diffuse optical tomography (DOT) has been studied for use in the detection of breast cancer, cerebral oxygenation, and cognitive brain signals. As optical imaging studies have increased significantly, acquiring imaging data in real time has become increasingly important. We have developed frequency-division multiplexing (FDM) DOT systems to analyze their performance with respect to acquisition ...
متن کاملA comparison study of linear reconstruction techniques for di use optical tomographic imaging of absorption coeÆcient
متن کامل
Reduction of image artifacts induced by change in the optode coupling in time-resolved diffuse optical tomography.
Tomographic images of the optical properties can be reconstructed using inversion algorithms for diffuse optical tomography (DOT); however, changes in the optode coupling that occurs while obtaining an object's measurements may often lead to the presence of artifacts in the reconstructed images. To reduce the number of artifacts induced by optode coupling, previous studies have introduced (unkn...
متن کاملComparison of linear reconstruction techniques for 3D DPDW imaging of absorption coefficient
In this paper we examine the performance of a number of linear techniques for reconstructing the 3-D distribution of absorption coefficient within a highly scattering medium using the diffuse photon density wave (DPDW) approximation. The simulation consists of a coplanar array of sources and detectors at the boundary of an infinite slab medium. The primary difficulty in the linear reconstructio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Physics in medicine and biology
دوره 45 4 شماره
صفحات -
تاریخ انتشار 2000